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Categories: Obesity
Published This outdated diabetes drug still has something to offer (via sciencedaily.com) Original source
Researchers have discovered the biochemical workings of an old-fashioned diabetes drug, and it's helping them develop new, safer alternatives.
Published Obese and overweight children at risk of iron deficiency (via sciencedaily.com) Original source
Children and young people who are overweight or obese are at significantly higher risk of iron deficiency, according to a study by nutritional scientists.
Published Few newly diagnosed type 2 diabetics succeed in losing weight -- weight gain linked to much higher risk of complications (via sciencedaily.com) Original source
A register-based study identified three distinct BMI trajectory groups among patients with newly diagnosed type 2 diabetes. In a four-year follow-up, most patients followed a stable trajectory without much weight change. Only 10% of patients lost weight, whereas 3% gained weight. Mean BMI exceeded the threshold of obesity in all groups at baseline. Weight loss is a central treatment goal in type 2 diabetes, but the study shows that few patients succeed in it.
Published Feeding the lonely brain (via sciencedaily.com) Original source
A new study has found that women who perceive themselves to be lonely exhibited activity in regions of the brain associated with cravings and motivation towards eating especially when shown pictures of high calorie foods such as sugary foods.
Published Pilot study shows ketogenic diet improves severe mental illness (via sciencedaily.com) Original source
A small clinical trial found that the metabolic effects of a ketogenic diet may help stabilize the brain.
Published Women with obesity do not need to gain weight during pregnancy, new study suggests (via sciencedaily.com) Original source
The guidelines for weight gain during pregnancy in obese women have long been questioned. New research supports the idea of lowering or removing the current recommendation of a weight gain of at least 5 kg.
Published Do sweeteners increase your appetite? New evidence from randomised controlled trial says no (via sciencedaily.com) Original source
Replacing sugar with artificial and natural sweeteners in foods does not make people hungrier -- and also helps to reduce blood sugar levels, a significant new study has found. The double blind randomized controlled trial found that consuming food containing sweeteners produced a similar reduction in appetite sensations and appetite-related hormone responses as sugary foods -- and provides some benefits such as lowering blood sugar, which may be particularly important in people at risk of developing type 2 diabetes. The use of sweeteners in place of sugar in foods can be controversial due to conflicting reports about their potential to increase appetite. Previous studies have been carried out but did not provide robust evidence. However, the researchers say their study, which meets the gold standard level of proof in scientific investigation, provides very strong evidence that sweeteners and sweetness enhancers do not negatively impact appetite and are beneficial for reducing sugar intake.
Published More than one billion people around the globe are facing obesity (via sciencedaily.com) Original source
The prevalence of malnutrition across the globe was shared by the NCD Risk Factor Collaboration, a network of health scientists from around the world who provide and evaluate data on major risk factors for all countries, in collaboration with the World Health Organization. The network participants reviewed body mass index data from more than 3,600 studies from 1990 to 2022, determining the rates of malnutrition, either from obesity or underweight, for all countries, and the degree to which the data has changed through the years.
Published Less obesity in 3- and 4-year-olds after the pandemic, Swedish study finds (via sciencedaily.com) Original source
The prevalence of overweight and obesity in the group of 3- and 4-year-olds in Sweden has decreased after the pandemic. The increase during the pandemic thus appears to have been temporary, according to a new study.
Published Metformin during pregnancy affects the brain development in offspring mice, study finds (via sciencedaily.com) Original source
With the rise in gestational diabetes and metabolic disorders during pregnancy, metformin is also being prescribed more frequently. Although it is known that the oral antidiabetic agent can cross the placental barrier, the impacts on the brain development of the child are largely unknown. Researchers have now been able to demonstrate in a mouse model that although metformin has positive effects in pregnant animals, it does not in the offspring.
Published Keto diet prevents early memory decline in mice (via sciencedaily.com) Original source
A new study shows the keto diet prevents early memory decline in mice. A molecule in the diet plays a key role in slowing Alzheimer's disease.
Published Fiber, genes and the gut microbiome: Study reveals possible triggers for inflammatory bowel disease (via sciencedaily.com) Original source
A new study finds a complex interplay between diet, genes, and the gut microbiota that could explain why IBD develops.
Published Kallistatin contributes to the beneficial metabolic effects of weight loss (via sciencedaily.com) Original source
After weight loss, people with overweight and obesity express more of the protein Kallistatin in subcutaneous white adipose tissue. Kallistatin improves metabolism and could open up new therapeutic options for people with obesity and type 2 diabetes in future.
Published Fatty food before surgery may impair memory in old, young adults (via sciencedaily.com) Original source
Eating fatty food in the days leading up to surgery may prompt a heightened inflammatory response in the brain that interferes for weeks with memory-related cognitive function in older adults -- and, new research in animals suggests, even in young adults.
Published Middle-age obesity is caused by changes in the shape of neurons in the brain (via sciencedaily.com) Original source
Researchers discovered a mechanism behind middle-age obesity in rat brains. They believe that a similar mechanism exists in humans as well. This discovery may lead to improvements in preventing obesity and metabolic syndrome.
Published Maternal obesity may promote liver cancer (via sciencedaily.com) Original source
Obesity, which could reach 50% of the population in certain developed countries by 2030, is a major public health concern. It not only affects the health of those who suffer from it, but could also have serious consequences for their offspring. Scientists have studied the impact of maternal obesity on the risk of developing liver disease and liver cancer. Using an animal model, the team discovered that this risk was indeed much higher in the offspring of mothers suffering from obesity.
Published Sweetened drinks linked to atrial fibrillation risk (via sciencedaily.com) Original source
An analysis of health data in the UK Biobank found a 20% higher risk of irregular heart rhythm, known as atrial fibrillation, among people who said they drank two liters or more per week (about 67 ounces) of artificially sweetened drinks. The risk was 10% higher among people who said they drank similar amounts of sugar-sweetened beverages.
Published Waist-to-height ratio detects fat obesity in children and adolescents significantly better than BMI (via sciencedaily.com) Original source
An inexpensive measure of obesity in children and adolescents that could replace body mass index (BMI) has been identified in a new study as waist circumference-to-height ratio. This measure detected excess fat mass and distinguished fat mass from muscle mass in children and adolescents more accurately than BMI.
Published Study identifies multi-organ response to seven days without food (via sciencedaily.com) Original source
New findings reveal that the body undergoes significant, systematic changes across multiple organs during prolonged periods of fasting. The results demonstrate evidence of health benefits beyond weight loss, but also show that any potentially health-altering changes appear to occur only after three days without food.
Published BPA exposure linked to gut microbiota, childhood obesity in new study (via sciencedaily.com) Original source
Researchers found more unique bacteria taxa in children of normal weight than in overweight or obese children. The findings suggest that BPA exposure could promote different microbial communities in normal weight children than those in children with obesity or who are overweight.