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Categories: Diabetes
Published Global research team finds no clear link between maternal diabetes during pregnancy and ADHD in children
(via sciencedaily.com) Original source An international research team has just provided valuable evidence through a 20-year longitudinal study to address the longstanding debate concerning the potential impact of maternal diabetes on attention-deficit/hyperactivity disorder (ADHD) in children. This study, analysing real-world data from over 3.6 million mother-baby pairs in China's Hong Kong, Taiwan, New Zealand, Finland, Iceland, Norway and Sweden, showed that maternal diabetes during pregnancy is unlikely to be a direct cause of ADHD.
Published Beating back bitter taste in medicine
(via sciencedaily.com) Original source The bitter taste of certain drugs is a barrier to taking some medications as prescribed, especially for people who are particularly sensitive to bitter taste. A team found that the diabetes drug rosiglitazone could partially block the bitter taste of some especially bad-tasting medications. The hope is that repurposed drugs could be added in small doses to other medicines to make them less bitter and taste better, thereby encouraging compliance with bitter drug regimens.
Published Few newly diagnosed type 2 diabetics succeed in losing weight -- weight gain linked to much higher risk of complications
(via sciencedaily.com) Original source A register-based study identified three distinct BMI trajectory groups among patients with newly diagnosed type 2 diabetes. In a four-year follow-up, most patients followed a stable trajectory without much weight change. Only 10% of patients lost weight, whereas 3% gained weight. Mean BMI exceeded the threshold of obesity in all groups at baseline. Weight loss is a central treatment goal in type 2 diabetes, but the study shows that few patients succeed in it.
Published Study finds less invasive, safer option for removing benign pancreatic tumors
(via sciencedaily.com) Original source Researchers describe a new technique for the minimally invasive removal of benign tumors located in the challenging posterior head of the pancreas (right side of abdomen, nestled in the curve of the duodenum (or first part of the small intestine). The technique, called the retro-laparoscopic approach, allows surgeons to safely and effectively remove these tumors without removing healthy pancreatic tissue, thereby preserving organ functionality.
Published Large language models respond differently based on user's motivation
(via sciencedaily.com) Original source A new study reveals how large language models (LLMs) respond to different motivational states. In their evaluation of three LLM-based generative conversational agents (GAs)--ChatGPT, Google Bard, and Llama 2, scientists found that while GAs are able to identify users' motivation states and provide relevant information when individuals have established goals, they are less likely to provide guidance when the users are hesitant or ambivalent about changing their behavior.
Published Wound treatment gel fights the battle against antibacterial resistance
(via sciencedaily.com) Original source Polymer-based hydrogels are used to treat skin ailments and in tissue engineering because of their ability to retain water, deliver drugs into wounds, and biodegrade. However, they are complicated to manufacture and not very resilient to external forces like rubbing against clothing, sheets, or wound dressings. Scientists have now created a hydrogel enhanced with the amino acid polylysine and blood plasma that is easier to synthesize, contains natural antibiotic properties, and promotes cell growth.
Published Do sweeteners increase your appetite? New evidence from randomised controlled trial says no
(via sciencedaily.com) Original source Replacing sugar with artificial and natural sweeteners in foods does not make people hungrier -- and also helps to reduce blood sugar levels, a significant new study has found. The double blind randomized controlled trial found that consuming food containing sweeteners produced a similar reduction in appetite sensations and appetite-related hormone responses as sugary foods -- and provides some benefits such as lowering blood sugar, which may be particularly important in people at risk of developing type 2 diabetes. The use of sweeteners in place of sugar in foods can be controversial due to conflicting reports about their potential to increase appetite. Previous studies have been carried out but did not provide robust evidence. However, the researchers say their study, which meets the gold standard level of proof in scientific investigation, provides very strong evidence that sweeteners and sweetness enhancers do not negatively impact appetite and are beneficial for reducing sugar intake.
Published For younger women, mental health now may predict heart health later
(via sciencedaily.com) Original source Younger women are generally thought to have a low risk of heart disease, but new research urges clinicians to revisit that assumption, especially for women who suffer from certain mental health conditions. A new study found that having anxiety or depression could accelerate the development of cardiovascular risk factors among young and middle-aged women.
Published Eggs may not be bad for your heart after all
(via sciencedaily.com) Original source Whether you like your eggs sunny-side up, hard boiled or scrambled, many hesitate to eat them amid concerns that eggs may raise cholesterol levels and be bad for heart health. However, results from a prospective, controlled trial show that over a four-month period cholesterol levels were similar among people who ate fortified eggs most days of the week compared with those who didn't eat eggs.
Published Miscarriages linked to health risks in later pregnancies
(via sciencedaily.com) Original source Researchers analyzed 52 studies involving more than 4 million pregnancies across 22 countries to investigate the health impacts of miscarriage, abortion and recurrent pregnancy loss (more than two miscarriages in succession) on subsequent pregnancies. The study found different health risks for each group.
Published Clear shift in arterial diseases in diabetes
(via sciencedaily.com) Original source There has been a redistribution in the risk of arterial disease in type 1 and 2 diabetes. The risks of heart attack and stroke have decreased significantly, while complications in more peripheral vessels have increased in relative importance, according to new studies.
Published Risk factors for faster aging in the brain revealed in new study
(via sciencedaily.com) Original source Researchers have used data from UK Biobank participants to reveal that diabetes, traffic-related air pollution and alcohol intake are the most harmful out of 15 modifiable risk factors for dementia.
Published Discovery has potential to solve the billion-dollar global cost of poorly managed wound healing
(via sciencedaily.com) Original source Scientists have uncovered a key step in the wound healing process that becomes disabled in diseases like diabetes and aging, contributing to a global healthcare cost of managing poorly healing wounds exceeding $250 billion a year. Importantly, the research reveals a molecule involved in the healing of tissues that -- when injected into animal models -- leads to a drastic acceleration of wound closure, up to 2.5 times faster, and 1.6 times more muscle regeneration.
Published Metformin during pregnancy affects the brain development in offspring mice, study finds
(via sciencedaily.com) Original source With the rise in gestational diabetes and metabolic disorders during pregnancy, metformin is also being prescribed more frequently. Although it is known that the oral antidiabetic agent can cross the placental barrier, the impacts on the brain development of the child are largely unknown. Researchers have now been able to demonstrate in a mouse model that although metformin has positive effects in pregnant animals, it does not in the offspring.
Published Insulin affects the recycling of cellular power plants
(via sciencedaily.com) Original source In nerve cells, the hormone regulates whether mitochondria are shut down or kept running.
Published Kallistatin contributes to the beneficial metabolic effects of weight loss
(via sciencedaily.com) Original source After weight loss, people with overweight and obesity express more of the protein Kallistatin in subcutaneous white adipose tissue. Kallistatin improves metabolism and could open up new therapeutic options for people with obesity and type 2 diabetes in future.
Published Study with innovative insights into the heterogeneity of type 2 diabetes
(via sciencedaily.com) Original source A landmark study sheds new light on the heterogeneity of type 2 diabetes. The researchers employed an innovative algorithm to stratify people with type 2 diabetes using routine data and thus visualize the metabolic diversity of diabetes.
Published Potential novel biomarkers of coronary heart disease discovered
(via sciencedaily.com) Original source Coronary heart disease is a major global health problem, especially among people with type 2 diabetes. Researchers have identified novel protein biomarkers that are associated with the development of CHD in people with and without diabetes.
Published Revolutionary chronic wound treatment could help millions
(via sciencedaily.com) Original source An effective treatment for chronic wounds that does not involve antibiotics, but an ionised gas to activate a wound dressing, has been developed by a team of international scientists.
Published Milk to the rescue for diabetics? Cow produces human insulin in milk
(via sciencedaily.com) Original source An unassuming brown bovine from the south of Brazil has made history as the first transgenic cow capable of producing human insulin in her milk. The advancement could herald a new era in insulin production, one day eliminating drug scarcity and high costs for people living with diabetes.