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Categories: Skin Care

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A study has now successfully controlled the effects of collagen hypersecretion at the cellular level. The experimental treatment consists of designer peptides which interrupt the interaction between TANGO1 and cTAGE5, two proteins important for collagen secretion. Experiments with patient-derived human cells and zebrafish showed the peptides are effective, non-toxic, and their effects reversible. The results pave the way for the development of new treatments that improve the cosmetic effects of scarring, relieve the symptoms of autoimmune diseases such as scleroderma, or help prevent the development of fibrosis, a more serious condition attributed to 45% of deaths in the industrialized world.

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A research team has synthesized a lysin that during in vitro experiments targets bacteria responsible for producing odors in human armpits.

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Clarifying the cause of a skin disease led to the discovery of a new disease-causing gene, a new category of diseases, and new perspectives for both counseling and therapy. The discovery is the first time that epigenetic silencing, the 'switching off' of an otherwise intact gene, has been recognized as the cause for a skin disease.

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Toxic chemicals used to flame-proof plastic materials can be absorbed into the body through skin, via contact with microplastics, new research shows.

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Polymer-based hydrogels are used to treat skin ailments and in tissue engineering because of their ability to retain water, deliver drugs into wounds, and biodegrade. However, they are complicated to manufacture and not very resilient to external forces like rubbing against clothing, sheets, or wound dressings. Scientists have now created a hydrogel enhanced with the amino acid polylysine and blood plasma that is easier to synthesize, contains natural antibiotic properties, and promotes cell growth.

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Scientists have uncovered a key step in the wound healing process that becomes disabled in diseases like diabetes and aging, contributing to a global healthcare cost of managing poorly healing wounds exceeding $250 billion a year. Importantly, the research reveals a molecule involved in the healing of tissues that -- when injected into animal models -- leads to a drastic acceleration of wound closure, up to 2.5 times faster, and 1.6 times more muscle regeneration.

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Scientists have discovered a gene mutation is responsible for causing psoriasis -- a chronic inflammatory skin disease that causes patients to develop red, scaly and itchy patches across their body. According to researchers, if two copies of this mutated gene (known as IKBKB) are present, patients with psoriasis may go on to develop psoriatic arthritis, leaving them with joint pain, stiffness and swelling. It's hoped the findings will lead to improved diagnosis and treatment for patients with psoriasis and psoriatic arthritis -- conditions that patients say carry stigma in the community.

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A mobile app that uses artificial intelligence, AI, to analyze images of suspected skin lesions can diagnose melanoma with very high precision, according to a new study.

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Researchers have developed a photoacoustic imaging watch for high-resolution imaging of blood vessels in the skin. The wearable device could offer a non-invasive way to monitor hemodynamic indicators such as heart rate, blood pressure and oxygen saturation that can indicate how well a person's heart is working.

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New research describes the science behind a promising technique to treat infertility by turning a skin cell into an egg that is capable of producing viable embryos. The technique could be used by women of advanced maternal age or for those who are unable to produce viable eggs due to previous treatment for cancer or other causes. It also raises the possibility of men in same-sex relationships having children who are genetically related to both parents.

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Retinoic acid, the active state of Vitamin A, appears to regulate how stem cells enter and exit a transient state central to their role in wound repair.

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Fat tissue holds the key to 3D printing layered living skin and potentially hair follicles, according to researchers who recently harnessed fat cells and supporting structures from clinically procured human tissue to precisely correct injuries in rats. The advancement could have implications for reconstructive facial surgery and even hair growth treatments for humans.

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Keratin microsphere gel, consisting of keratin-based microspheres that swell in water to form a gel, has shown efficacy in promoting hair follicle growth in murine models. Its potential application as an active ingredient in hair regrowth treatments with minimal side effects is anticipated.

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A new technique for electro-spinning sponges has allowed scientists to directly produce 3D scaffolds -- on which skin grafts could be grown from the patient's own skin.

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A new study examines dermal injections and their impact on skin aging.

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Medical researchers have found a peptide which, when administered intravenously, homes in on the new blood vessels that are forming in damaged tissue. The peptide has been used as a delivery vehicle for therapeutics targeted at regenerating tissues. A new study has discovered that the peptide activates the natural healing mechanism in the tissue, accelerating regeneration. The finding opens new opportunities to treat not only skin wounds, but also any injuries resulting from accidents and traumas, such as ruptured muscles and fractured bones.

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A study has demonstrated that the appearance of ageing skin looks noticeably different compared to younger skin, when examined under polarized laser light. The scientists believe that their new finding could pave the way for new, non-invasive light-based techniques to detect diseases, including cancer, in older individuals. This could significantly enhance early-stage treatment options for various skin conditions.

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Doctors do not perform as well diagnosing skin diseases when the patient has darker skin, according to a new study. The researchers found assistance from artificial intelligence could improve doctors' accuracy, but those improvements were greater in patients with lighter skin.

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New findings report that a class of small RNAs (microRNAs), microRNA-29, can restore normal skin structure rather than producing a wound closure by a connective tissue (scar). Any improvement of normal skin repair would benefit many patients affected by large-area or deep wounds prone to dysfunctional scarring.

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A joint research team has developed a stretchable and adhesive microneedle sensor that can be attached to the skin and stably measure high-quality electrophysiological signals for a long period of time.