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Categories: Today's Healthcare
Published A new anticoagulant with no risk of bleeding
(via sciencedaily.com) Original source Anticoagulant treatments are crucial for managing many conditions, such as heart disease, stroke and venous thrombosis. Current options, however, carry an inherent risk of serious bleeding due to trauma or unforeseen events. A team has developed a new anticoagulant, designed to have an on-demand reversible activity, with a fast-acting 'antidote'. This approach could revolutionize the use of anticoagulants in surgery or other applications. The mechanism of activation and deactivation of the active principle could also be used in immunotherapy.
Published Tsetse fly protein provides anticoagulant with its own on-off switch
(via sciencedaily.com) Original source A completely novel way to develop 'surpamolecules' for drug discovery could have application in immunotherapy as well as this breakthrough design for an anticoagulant with on-demand reversibility.
Published Blood samples enhance B-cell lymphoma diagnostics and prognosis
(via sciencedaily.com) Original source A recently completed study indicates that circulatory protein levels can provide important information for increasingly accurate diagnoses and personalised care in patients with aggressive B-cell lymphoma. Researchers identified a specific protein profile linked to more severe disease.
Published How geography acts as a structural determinant of health
(via sciencedaily.com) Original source In unincorporated communities in the United States-Mexico borderlands, historically and socially marginalized populations become invisible to the healthcare system, showing that geography acts as a structural determinant of health for low-income populations.
Published Air pollution and depression linked with heart disease deaths in middle-aged adults
(via sciencedaily.com) Original source A study in more than 3,000 US counties, with 315 million residents, has suggested that air pollution is linked with stress and depression, putting under-65-year-olds at increased risk of dying from cardiovascular disease.
Published Advance in the treatment of acute heart failure identified
(via sciencedaily.com) Original source A multicenter study has identified a potential new treatment for acute heart failure, a leading cause of hospitalization and death.
Published Shoulder surgeons should rethink a common practice, study suggests
(via sciencedaily.com) Original source Many surgeons remove the bursa when repairing rotator cuff injuries, but a new animal study suggests that the small tissue helps with healing.
Published New tool helps identify babies at high-risk for RSV
(via sciencedaily.com) Original source A new tool to identify infants most at risk for severe respiratory syncytial virus (RSV) illness could aid pediatricians in prioritizing children under 1 to receive a preventive medication before RSV season (October-April), according to new research.
Published Diamond dust shines bright in Magnetic Resonance Imaging
(via sciencedaily.com) Original source An unexpected discovery surprised a scientist: nanometer-sized diamond particles, which were intended for a completely different purpose, shone brightly in a magnetic resonance imaging experiment -- much brighter than the actual contrast agent, the heavy metal gadolinium. Could diamond dust -- in addition to its use in drug delivery to treat tumor cells -- one day become a novel contrast agent used for MRI?
Published Physical activity in nature helps prevent several diseases, including depression and type 2 diabetes
(via sciencedaily.com) Original source Physical activity in natural environments prevent almost 13,000 cases of non-communicable diseases a year in England and save treatment costs of more than 100 million, new research has found.
Published Simplified diagnosis of rare eye diseases
(via sciencedaily.com) Original source Uveitis is a rare inflammatory eye disease. Posterior and panuveitis in particular are associated with a poor prognosis and a protracted course of the disease. Diagnosis and monitoring can be challenging for healthcare professionals. Fundus autofluorescence (FAF) is a fast and non-invasive imaging technique that supports this. Researchers have drafted a review on how FAF can facilitate the diagnosis and monitoring of posterior uveitis and panuveitis.
Published AI in medicine: The causality frontier
(via sciencedaily.com) Original source Machines can learn not only to make predictions, but also to handle causal relationships. An international research team shows how this could make therapies safer, more efficient, and more individualized.
Published National trial safely scaled back prescribing of a powerful antipsychotic for the elderly
(via sciencedaily.com) Original source Warning letters can safely cut prescribing of a powerful but risky antipsychotic, according to a new study. Researchers used Medicare data to study the effects of the letters on hundreds of thousands of older adults with dementia. They found a significant and lasting reduction in prescribing but no signs of adverse effects on patient health.
Published For immigrants to Canada, risk of multiple sclerosis increases with proportion of life spent there, study finds
(via sciencedaily.com) Original source Immigrants to Canada who have spent a greater proportion of their lives in Canada have a greater risk of developing multiple sclerosis (MS) than people who have spent a smaller proportion of their lives there, according to a new study. The study does not prove that an increased proportion of life in Canada causes MS; it only shows an association.
Published Artificial intelligence can develop treatments to prevent 'superbugs'
(via sciencedaily.com) Original source Cleveland Clinic researchers developed an artficial intelligence (AI) model that can determine the best combination and timeline to use when prescribing drugs to treat a bacterial infection, based solely on how quickly the bacteria grow given certain perturbations. PNAS recently published their findings.
Published After spinal cord injury, neurons wreak havoc on metabolism
(via sciencedaily.com) Original source Conditions such as diabetes, heart attack and vascular diseases commonly diagnosed in people with spinal cord injuries can be traced to abnormal post-injury neuronal activity that causes abdominal fat tissue compounds to leak and pool in the liver and other organs, a new animal study has found.
Published A flexible microdisplay can monitor brain activity in real-time during brain surgery
(via sciencedaily.com) Original source A thin film that combines an electrode grid and LEDs can both track and produce a visual representation of the brain's activity in real-time during surgery -- a huge improvement over the current state of the art. The device is designed to provide neurosurgeons visual information about a patient's brain to monitor brain states during surgical interventions to remove brain lesions including tumors and epileptic tissue.
Published CAR T cell therapy targeting HER2 antigen shows promise against advanced sarcoma in phase I trial
(via sciencedaily.com) Original source Researchers have published results of a phase I clinical trial of a novel immunotherapy for high-risk sarcomas.
Published Positive effect of midazolam after cardiac arrest
(via sciencedaily.com) Original source If a patient is successfully resuscitated after a cardiac arrest and circulation resumes, they are not out of the woods yet. A number of factors can influence whether and how they survive the trauma in the subsequent phase. The administration of the anaesthetic midazolam has a positive effect, as shown by a multicenter study of 571 patients.
Published Treatment from female doctors leads to lower mortality and hospital readmission rates, study suggests
(via sciencedaily.com) Original source Patients have lower rates of mortality and hospital readmissions when treated by female physicians, with female patients benefitting more than their male counterparts, new research suggests.