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Child Development
Published

Large language models can't effectively recognize users' motivation, but can support behavior change for those ready to act      (via sciencedaily.com)     Original source 

Large language model-based chatbots can't effectively recognize users' motivation when they are hesitant about making healthy behavior changes, but they can support those who are committed to take action, say researchers.

Psychology Research
Published

Different brain structures in females lead to more severe cognitive deficits after concussion than males      (via sciencedaily.com)     Original source 

Important brain structures that are key for signaling in the brain are narrower and less dense in females, and more likely to be damaged by brain injuries, such as concussion. Long-term cognitive deficits occur when the signals between brain structures weaken due to the injury. The structural differences in male and female brains might explain why females are more prone to concussions and experience longer recovery from the injury than their male counterparts.

Chronic Illness
Published

The vicious cycle of protein clumping in Alzheimer's disease and normal aging      (via sciencedaily.com)     Original source 

To date, approaches to treatments for Alzheimer's disease have not addressed the contribution of protein insolubility as a general phenomenon, instead focusing on one or two insoluble proteins. Researchers have recently completed a systematic study in worms that paints an intricate picture of the connections between insoluble proteins in neurodegenerative diseases and aging. Furthermore, the work demonstrated an intervention that could reverse the toxic effects of the aggregates by boosting mitochondrial health.

Today's Healthcare
Published

Researchers wrestle with accuracy of AI technology used to create new drug candidates      (via sciencedaily.com)     Original source 

Researchers have determined that a protein prediction technology can yield accurate results in the hunt to efficiently find the best possible drug candidates for many conditions.

Chronic Illness
Published

New gene delivery vehicle shows promise for human brain gene therapy      (via sciencedaily.com)     Original source 

In an important step toward more effective gene therapies for brain diseases, researchers have engineered a gene-delivery vehicle that uses a human protein to efficiently cross the blood-brain barrier and deliver a disease-relevant gene to the brain in mice expressing the human protein. Because the vehicle binds to a well-studied protein in the blood-brain barrier, the scientists say it has a good chance at working in patients.

Child Development Psychology Research
Published

Singing repairs the language network of the brain after a cerebrovascular accident      (via sciencedaily.com)     Original source 

Singing rehabilitates speech production in post-stroke aphasia. Researchers investigated the rehabilitative effect of singing on the brain.

Chronic Illness
Published

Celiac disease: New findings on the effects of gluten      (via sciencedaily.com)     Original source 

Celiac disease is a chronic autoimmune condition that occurs in around one per cent of the world's population. It is triggered by the consumption of gluten proteins from wheat, barley, rye and some oats. A gluten-free diet protects celiac patients from severe intestinal damage.

Psychology Research Today's Healthcare
Published

Very early blood pressure control confers both benefits and harms in acute stroke      (via sciencedaily.com)     Original source 

Early identification of stroke type could be key to harnessing the benefits of very early in-ambulance blood pressure lowering treatment in patients with suspected acute stroke, according to new research.

Nutrition
Published

Why do we overindulge?      (via sciencedaily.com)     Original source 

If you tend to do other things or get distracted while eating dinner, you may be running the risk of over-consuming everyday pleasures later, possibly because the distraction caused you to enjoy yourself less, according to new research.

Diet and Weight Loss Dieting and Weight Control Nutrition Obesity Psychology Research
Published

'Trojan horse' weight loss drug more effective than available therapies      (via sciencedaily.com)     Original source 

A groundbreaking article describes a promising new therapy for obesity that leads to greater weight loss in mice than existing medications. The approach smuggles molecules into the brain's appetite center and affects the brain's neuroplasticity.

Relationships
Published

When saying 'please' is more strategic than magic      (via sciencedaily.com)     Original source 

By kindergarten age, most children have been taught that 'please' is a magic word. 'Please' is an expression of politeness that shows courtesy and respect, turning a potential demand into a request that will -- poof! -- magically be granted. But a new study on the ways people make requests of one another suggests that 'please' might not be an all-purpose marker of politeness, but rather a more focused, strategic tool to manage frictions or obstacles among family members, friends and even coworkers. The study shows that people say 'please' much less often than expected, and mostly when they expect a 'no' response is forthcoming.

Today's Healthcare
Published

Blood pressure drugs more than double bone-fracture risk in nursing home patients      (via sciencedaily.com)     Original source 

New research finds a link between common medications and life-threatening injuries.

Today's Healthcare
Published

Pre- and post-surgical immunotherapy improves outcomes for patients with operable lung cancer      (via sciencedaily.com)     Original source 

Compared with pre-surgical (neoadjuvant) chemotherapy alone, adding perioperative immunotherapy -- given before and after surgery -- significantly improved event-free survival (EFS) in patients with resectable early-stage non-small cell lung cancer(NSCLC), according to researchers.

Fertility Today's Healthcare
Published

Infertility treatment doubles the risk of postpartum heart disease      (via sciencedaily.com)     Original source 

Researchers tie infertility treatment to a particular risk for hypertensive diseases.

Obesity
Published

Two decades of studies suggest health benefits associated with plant-based diets      (via sciencedaily.com) 

Vegetarian and vegan diets are generally associated with better status on various medical factors linked to cardiovascular health and cancer risk, as well as lower risk of cardiovascular diseases, cancer, and death, according to a new review of 49 previously published papers.

Obesity
Published

Racial disparities in childhood obesity on the rise      (via sciencedaily.com)     Original source 

Among public school students in New York City, some of the greatest increases in childhood obesity in recent years were among those socioeconomic and demographic groups already bearing the greatest burden of obesity, including Black and Hispanic students and youth living in poverty, according to a new study.

Birth Defects Healthy Aging Psychology Research
Published

Research sheds light on how proteins linked to Alzheimer's disease influence neuronal growth      (via sciencedaily.com)     Original source 

New research has shed light in the complex interplay between cell proteins, and how they impact on neurons in neurodevelopmental disorders and Alzheimer's disease.

Today's Healthcare
Published

Exploring the mechanism behind drug eruptions in the skin      (via sciencedaily.com)     Original source 

Although drug eruptions are often linked to the human leukocyte antigen (HLA), the mechanism of its involvement in presenting symptoms of the skin remains unclear. In a recent study, researchers used genetically engineered mice to demonstrate the role of HLA in mediating intracellular reactions in keratinocytes, leading to drug eruptions in the skin. Their findings could lead to improved preventive and treatment measures for drug eruptions.

Fitness
Published

Longer sprint intervals can improve muscle oxygen utilization compared to shorter intervals      (via sciencedaily.com)     Original source 

Sprint interval training (SIT) is a form of exercise characterized by cycles of intense exercise which are interspersed by short durations of rest. In a recent study, researchers deep dive into the intricate connections among various parameters of SIT, such as duration and repetitions, and the resulting physiological responses. Their findings can aid in developing well-informed and tailored sprint training regimens that significantly benefit the modern-day population.

Chronic Illness Obesity
Published

Fighting fat and inflammation: Scientists develop powerful new compounds      (via sciencedaily.com)     Original source 

Obesity and inflammatory diseases are increasing in prevalence and contribute to the growing burden of lifestyle disorders such as diabetes and hypertension. There is a lack of naturally derived alternatives to tackle these issues. Researchers have synthesized novel amino acid derivatives of menthol and studied its properties. The menthyl esters showed exceptional anti-inflammatory and anti-obesity activities during preclinical studies and can be developed as therapeutic compounds with further research.