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Published Microarray patches safe and effective for vaccinating children, trial suggests (via sciencedaily.com) Original source
The first study of the use of microarray patches to vaccinate children has shown that the method is safe and induces strong immune responses. The phase 1/2 randomized trial compared results from the measles and rubella vaccine delivered by a microarray patch, a small sticking plaster-like device with an array of microscopic projections that painlessly penetrate the skin and deliver the vaccine, or by conventional injection with a needle and syringe.
Published Study finds school entry requirements linked to increased HPV vaccination rates (via sciencedaily.com) Original source
A new study shows that school entry requirements are linked to an increase in human papillomavirus (HPV) vaccinations.
Published Experimental type 1 diabetes drug shelters pancreas cells from immune system attack (via sciencedaily.com) Original source
Scientists say that an experimental monoclonal antibody drug called mAb43 appears to prevent and reverse the onset of clinical type 1 diabetes in mice, and in some cases, to lengthen the animals' lifespan.
Published AI algorithms can determine how well newborns nurse, study shows (via sciencedaily.com)
A modified pacifier and AI algorithms to analyze the data it produces could determine if newborns are learning the proper mechanics of nursing, a recent study shows. Specifically, the researchers measured if babies are generating enough suckling strength to breastfeed and whether they are suckling in a regular pattern based on eight independent parameters.
Published Cardio-fitness cuts death and disease by nearly 20% (via sciencedaily.com) Original source
Groundbreaking new research finds that an increased cardio fitness level will reduce your risk of death from any cause by nearly 20%.
Published Blood samples enhance B-cell lymphoma diagnostics and prognosis (via sciencedaily.com) Original source
A recently completed study indicates that circulatory protein levels can provide important information for increasingly accurate diagnoses and personalised care in patients with aggressive B-cell lymphoma. Researchers identified a specific protein profile linked to more severe disease.
Published Breakthrough in brown fat research: Researchers have found brown fat's 'off-switch' (via sciencedaily.com) Original source
Researchers have found a protein that is responsible for turning off brown fat activity. This new discovery could lead to a promising strategy for safely activating brown fat and tackling obesity and related health problems.
Published Breast cancer rates rising among Canadian women in their 20s, 30s and 40s (via sciencedaily.com) Original source
Rates of breast cancer in women under the age of 50 are rising in Canada according to a study which showed an increase in breast cancer diagnoses among females in their twenties, thirties, and forties.
Published How geography acts as a structural determinant of health (via sciencedaily.com) Original source
In unincorporated communities in the United States-Mexico borderlands, historically and socially marginalized populations become invisible to the healthcare system, showing that geography acts as a structural determinant of health for low-income populations.
Published Component of keto diet plus immunotherapy may reduce prostate cancer (via sciencedaily.com) Original source
Adding a pre-ketone supplement -- a component of a high-fat, low-carb ketogenic diet -- to a type of cancer therapy in a laboratory setting was highly effective for treating prostate cancer, researchers found.
Published Pregnancy cytokine levels impact fetal brain development and offspring behavior (via sciencedaily.com) Original source
Researchers have discovered in a preclinical model that cytokines, proteins that control immune response, circulating in maternal blood during pregnancy may mitigate an offspring's risk for psychiatric conditions. The findings are surprising because circulating maternal cytokines are at such low levels that they were not implicated in fetal brain development and offspring behavior before.
Published People with rare longevity mutation may also be protected from cardiovascular disease (via sciencedaily.com) Original source
Patients with growth hormone receptor deficiency, or Laron syndrome, appear to have lower than average risk factors for cardiovascular disease, according to a new study.
Published Air pollution and depression linked with heart disease deaths in middle-aged adults (via sciencedaily.com) Original source
A study in more than 3,000 US counties, with 315 million residents, has suggested that air pollution is linked with stress and depression, putting under-65-year-olds at increased risk of dying from cardiovascular disease.
Published Climb stairs to live longer (via sciencedaily.com) Original source
Climbing stairs is associated with a longer life, according to new research
Published Advance in the treatment of acute heart failure identified (via sciencedaily.com) Original source
A multicenter study has identified a potential new treatment for acute heart failure, a leading cause of hospitalization and death.
Published RNA modification is responsible for the disruption of mitochondrial protein synthesis in Alzheimer's disease (via sciencedaily.com) Original source
A team of researchers has identified a mechanism that causes mitochondrial dysfunction in Alzheimer's patients resulting in a reduction of the supply of energy to the brain.
Published Shoulder surgeons should rethink a common practice, study suggests (via sciencedaily.com) Original source
Many surgeons remove the bursa when repairing rotator cuff injuries, but a new animal study suggests that the small tissue helps with healing.
Published Vitamin D alters mouse gut bacteria to give better cancer immunity (via sciencedaily.com) Original source
Researchers have found that vitamin D encourages the growth of a type of gut bacteria in mice which improves immunity to cancer.
Published Food in sight? The liver is ready! (via sciencedaily.com) Original source
What happens in the body when we are hungry and see and smell food? A team of researchers has now been able to show in mice that adaptations in the liver mitochondria take place after only a few minutes. Stimulated by the activation of a group of nerve cells in the brain, the mitochondria of the liver cells change and prepare the liver for the adaptation of the sugar metabolism. The findings could open up new avenues for the treatment of type 2 diabetes.
Published New tool helps identify babies at high-risk for RSV (via sciencedaily.com) Original source
A new tool to identify infants most at risk for severe respiratory syncytial virus (RSV) illness could aid pediatricians in prioritizing children under 1 to receive a preventive medication before RSV season (October-April), according to new research.