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Engineers have discovered that some brain cells age more rapidly than others, and they are disproportionately abundant in individuals afflicted with Alzheimer's disease. Additionally, researchers observed male-female-specific differences in the aging process of certain brain cells, with the female cortex exhibiting a higher ratio of 'old' oligodendrocytes to 'old' neurons compared to the male cortex. The discoveries were made possible by a new technique called MUSIC (multinucleic acid interaction mapping in single cells), which allows researchers to peek inside individual brain cells and map out interactions between chromatin--which is the tightly coiled form of DNA -- and RNA.

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Researchers have discovered a distinct, secondary population of platelets that appears with aging and have hyperreactive behavior and unique molecular properties, which could make them easier to target with medication.

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Analysis of 1,392 patients with traumatic brain injuries (TBIs) found that some patients for whom life support was withdrawn may have survived and recovered some level of independence a few months after injury. Families are often asked to make decision to withdraw life support within 72 hours of a brain injury, and the new study suggests delaying decisions may be beneficial for some patients.

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Men with prostate cancer could significantly reduce the chances of the disease worsening by eating more fruits, vegetables, nuts, and olive oil, according to new research.

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Melanoma, an aggressive form of skin cancer that accounts for 75% of all skin-cancer-related deaths, is often detected later in people with darker skin complexions -- and the consequences can be devastating, a new study reveals.

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A breakthrough study features a biomedical engineering innovation with the potential to transform trauma care and surgical practices. A scientific research team has developed platelet-like particles that integrate into the body's clotting pathways to stop hemorrhage.

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Many artificial intelligence (AI) systems have already learned how to deceive humans, even systems that have been trained to be helpful and honest. Researchers describe the risks of deception by AI systems and call for governments to develop strong regulations to address this issue as soon as possible.

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Researchers have shed new light on the changes in metabolism that occur between birth and the presentation of autism spectrum disorder (ASD) later in childhood. The researchers discovered that a small number of biochemical pathways are responsible for the majority of these changes, which could help inform new early detection and prevention strategies for autism.

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The tool will help researchers better understand major challenges that afflict undernourished children, such as changes in cognitive development and higher infection rates.

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Discrimination may speed up the biological processes of aging, according to a new study.

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Researchers developed a potential new treatment for alopecia areata, an autoimmune disorder that causes hair loss. The microneedle patch delivers immune-regulating molecules that can teach T cells not to attack hair follicles, helping hair regrow.

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Just a few days on a night shift schedule throws off protein rhythms related to blood glucose regulation, energy metabolism and inflammation, processes that can influence the development of chronic metabolic conditions. The finding provides new clues as to why night shift workers are more prone to diabetes, obesity and other metabolic disorders. Though more research is needed, the researchers said the study shows that these disrupted rhythms can be seen in as little as three days, which suggests early intervention to prevent diabetes and obesity is possible. Such intervention could also help lower the risk of heart disease and stroke, which is elevated in night shift workers as well.

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Researchers present Tripath: new, deep learning models that can use 3D pathology datasets to make clinical outcome predictions. The research team imaged curated prostate cancer specimens, using two 3D high-resolution imaging techniques. The models were then trained to predict prostate cancer recurrence risk on volumetric human tissue biopsies. By comprehensively capturing 3D morphologies from the entire tissue volume, Tripath performed better than pathologists and outperformed deep learning models that rely on 2D morphology and thin tissue slices.

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A new study shows that a mild stress is enough to trigger post-traumatic stress disorder (PTSD) in mouse models of autism spectrum disorder (ASD). Researchers demonstrated that the two disorders share a reciprocal relationship, identifying a predisposition to PTSD in ASD, and discovering that core autism traits are worsened when traumatic memories are formed.

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A research team has identified the primary cause of sensory hypersensitivity in a mouse model of autism spectrum disorders (ASD).

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Aging clocks can measure the biological age of humans with high precision. Biological age can be influenced by environmental factors such as smoking or diet, thus deviating from the chronological age that is calculated using the date of birth. The precision of these aging clocks suggests that the aging process follows a program. Scientists have now discovered that aging clocks actually measure the increase in stochastic changes in cells.

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Researchers lay out the need for design safety protocols that prevent the emerging 'digital afterlife industry' causing social and psychological harm.

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Researcher found that exposed individuals with confirmed TB infection -- i.e. a positive skin or blood test -- should receive priority treatment in settings with a low prevalence of the disease, regardless of their age. However, in high-burden settings, all exposed individuals should be considered for preventative treatment, even without a confirmed infection. This strategy can help end the tuberculosis epidemic and support global public health efforts to reduce TB mortality by 95 percent by 2035 (from 2015 estimates).

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Neuropathy, the nerve damage that causes pain and numbness in the feet and hands and can eventually lead to falls, infection and even amputation, is very common and underdiagnosed, according to a new study.

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A tiny, flexible electronic device that wraps around the spinal cord could represent a new approach to the treatment of spinal injuries, which can cause profound disability and paralysis. A team of engineers, neuroscientists and surgeons developed the devices and used them to record the nerve signals going back and forth between the brain and the spinal cord. Unlike current approaches, the new devices can record 360-degree information, giving a complete picture of spinal cord activity.