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In people's early- to mid-20s, they reach what is called peak bone mineral density, which is higher for men than it is for women, according to researchers. This peak is one of the main determinants of fracture risk later in life. After reaching this peak, a person's bone density remains roughly stable for a couple of decades. Then, when women enter the menopausal transition, they experience accelerated bone loss. Men also experience bone density decline as they age. Sleep patterns also evolve over time.

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Researchers have discovered a protein marker to help identify cells able to repopulate in patients with damaged blood vessels. Their findings could lead to new therapies for people with endothelial dysfunction, a type of disorder that contributes to coronary artery disease that may occlude with plaque and lack ability to carry sufficient blood into the heart tissue causing a heart attack.

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Fatty liver disease often leads to chronic liver inflammation and can even result in liver cancer. Scientists have now shown in mice that intermittent fasting on a 5:2 schedule can halt this development. The fasting regime reduces the development of liver cancer in mice with pre-existing liver inflammation. The researchers identified two proteins in liver cells that are jointly responsible for the protective effect of fasting. An approved drug can partially mimic this effect.

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The world's largest study of cerebral palsy (CP) genetics has discovered genetic defects are most likely responsible for more than a quarter of cases in Chinese children, rather than a lack of oxygen at birth as previously thought.

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In an exploratory clinical trial, four male patients diagnosed with major depressive disorder underwent eight weeks of treatment with a device that generates a low-frequency ultralow magnetic field environment (ELF-ELME). An improvement in depressive symptoms was observed, with no adverse effects, among all patients. If the efficacy of the device can be confirmed in larger clinical trials with a control group, this therapy could serve as an alternative treatment for patients who do not want to take antidepressant medications.

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Study suggests more extensive screening method in the first trimester of pregnancy may improve detection of preeclampsia.

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The toll cancer takes on lives in the U.S. has declined during the last 28 years, but not equitably. Disparities persist in many historically marginalized communities -- including communities disadvantaged by race, socioeconomic status, orientation or gender identity, and geographic location -- despite community outreach and engagement programs designed to address them.

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A new study provides some of the clearest and most comprehensive evidence to date on what is known about stress physiology and 'epigenetic programming.'

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A new study has revealed that areas of age-related damage in the brain relate to motor outcomes after a stroke -- a phenomenon that may be under-recognized in stroke research. The new observational study looked at the relationship between stroke recovery and white matter hyper-intensities (WMHs) -- areas of age-related damage in the brain's white matter, which represent vascular dysfunction and are known to impact cognitive functions.

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The famous axiom 'the enemy of my enemy is my friend' is part of Austrian psychologist Fritz Heider's social balance theory, introduced in the 1940s. Previous studies have tried to model social networks based in famous theory but results remained controversial. New model takes into account two key pieces simultaneously: Not everyone knows everyone else in a social network, and some people are friendlier than others. With those two constraints, large-scale social networks consistently align with social balance theory. Model has broad applications for exploring political polarization, neural networks, drug interactions and more.

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New research examines how the bacteria Escherichia coli, or E. coli -- responsible for most UTIs -- is able to use host nutrients to reproduce at an extraordinarily rapid pace during infection despite the near sterile environment of fresh urine.

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The placenta's response to infections from malaria, toxoplasmosis and listeria has been mapped in high resolution, possibly paving the way for new treatment options.

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A new study sheds light on the complexities of achieving optimal vitamin D status across diverse populations. Despite substantial research on the determinants of vitamin D, levels of vitamin D deficiency remain high. Researchers believe their findings have significant implications for the development of tailored recommendations for vitamin D supplementation.

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A new study provides compelling evidence that genome-matched treatments can provide significant patient benefit.

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A breakthrough study appears to overcome difficulties that have long frustrated previous attempts to reverse a form of nerve damage that robs people with MS of motor control and gradually blunts cognitive functions for many people as they age.

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Some neurological disorders can be improved through photobiomodulation, a non-invasive technique based on the application of low-intensity light to stimulate altered functions in specific regions of the body. Now, a study reveals how photobiomodulation applied to the brain-gut axis is effective in recovering some cognitive alterations and sequelae caused by chronic stress. The study opens up new perspectives for applying the technique in future therapies for the treatment of neurological diseases in patients.

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Blood vessels in the lungs aren't like the others in the body. This difference becomes clear in pulmonary hypertension, in which only the lungs' blood vessels stiffen progressively, leading to chronic lung disease, heart failure and death. The underlying reasons for this organ-specific vessel stiffening remained a mystery until researchers made a surprising discovery about these blood vessel cells in patients with pulmonary hypertension -- they're hungry.

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Vigorous exercise burns fat more in males than in females, but the benefits of exercise are broad for everyone.

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A new prototype sensor is capable of detecting errors in MRI scans using laser light and gas. The new sensor can thereby do what is impossible for current electrical sensors -- and hopefully pave the way for MRI scans that are better, cheaper and faster.

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Researchers are on a mission to kill drug-resistant bacteria, and a new study has identified a therapy that can penetrate the slime that such infections use to protect themselves from antibiotics.Researchers have shown that an antimicrobial peptide from cows has potential for treating incurable infections from the bacterium Klebsiella pneumoniae. The bacteria, commonly found in the intestines, is usually harmless. It becomes a health hazard when it enters other parts of the body and can cause pneumonia, urinary tract and wound infections. Those at highest risk include seniors and patients with other health problems such as diabetes, cancer, kidney failure and liver disease.