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Published Food in sight? The liver is ready!
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What happens in the body when we are hungry and see and smell food? A team of researchers has now been able to show in mice that adaptations in the liver mitochondria take place after only a few minutes. Stimulated by the activation of a group of nerve cells in the brain, the mitochondria of the liver cells change and prepare the liver for the adaptation of the sugar metabolism. The findings could open up new avenues for the treatment of type 2 diabetes.
Published Solving the riddle of the sphingolipids in coronary artery disease
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Investigators have uncovered a way to unleash in blood vessels the protective effects of a type of fat-related molecule known as a sphingolipid, suggesting a promising new strategy for the treatment of coronary artery disease.
Published It takes two to TANGO: New strategy to tackle fibrosis and scarring
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A study has now successfully controlled the effects of collagen hypersecretion at the cellular level. The experimental treatment consists of designer peptides which interrupt the interaction between TANGO1 and cTAGE5, two proteins important for collagen secretion. Experiments with patient-derived human cells and zebrafish showed the peptides are effective, non-toxic, and their effects reversible. The results pave the way for the development of new treatments that improve the cosmetic effects of scarring, relieve the symptoms of autoimmune diseases such as scleroderma, or help prevent the development of fibrosis, a more serious condition attributed to 45% of deaths in the industrialized world.
Published Social media can be used to increase fruit and vegetable intake in young people
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Researchers have found that people following healthy eating accounts on social media for as little as two weeks ate more fruit and vegetables and less junk food.
Published Low intensity exercise linked to reduced depression
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New research has found a significant association between participating in low to moderate intensity exercise and reduced rates of depression.
Published Apply single-cell analysis to reveal mechanisms of a common complication of Crohn's disease
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Study identifies key pathways underlying perianal fistula, a disease complication that is more prevalent and severe in African American populations.
Published Genetics predict type 2 diabetes risk and disparities in childhood cancer survivors
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Learn how ancestry changes genetic risk variants' impact on type 2 diabetes in childhood cancer survivors & alkylating agent exposure magnifies diabetes risk. Learn how ancestry changes genetic risk variants' impact on type 2 diabetes in childhood cancer survivors & alkylating agent exposure magnifies diabetes risk.
Published Don't be a stranger -- study finds rekindling old friendships as scary as making new ones
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Psychologists have found that people are as hesitant to reach out to an old friend as they are to strike up a conversation with a stranger, even when they had the capacity and desire to do so.
Published New study uncovers lasting financial hardship associated with cancer diagnosis for working-age adults in the U.S.
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A new study highlights the lasting financial impact of a cancer diagnosis for many working-age adults and their families in the United States. It shows a cancer diagnosis and the time required for its treatment can result in employment disruptions, loss of household income and loss of employment-based health insurance coverage, leading to financial hardship.
Published Innovative microscopy demystifies metabolism of Alzheimer's
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Using state-of-the-art microscopy techniques, researchers have shed new light on the underlying mechanisms driving Alzheimer's disease.
Published In the brain, bursts of beta rhythms implement cognitive control
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Bursts of brain rhythms with 'beta' frequencies control where and when neurons in the cortex process sensory information and plan responses. Studying these bursts would improve understanding of cognition and clinical disorders, researchers argue in a new review.
Published Hey Dave, I've got an idea for you: What's the potential of AI-led workshopping?
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Sure, ChatGPT can write a poem about your pet in the style of T.S Eliot, but generative artificial intelligence (AI) chatbots have a potentially more useful role to play in idea generation according to a new study.
Published Odor-causing bacteria in armpits targeted using bacteriophage-derived lysin
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A research team has synthesized a lysin that during in vitro experiments targets bacteria responsible for producing odors in human armpits.
Published Dengue fever infections have negative impacts on infant health for three years
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Dengue infections in pregnant women may have a negative impact on the first years of children's lives, new research has found.
Published Exploring brain synchronization patterns during social interactions
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Social interactions synchronize brain activity within individuals and between individuals. In a new study, researchers compared brain synchronization between pairs of people with relatively strong social ties (acquaintance pairs) and pairs with almost no social ties (stranger pairs). The study found that during a cooperative task, the stranger pairs exhibited more closely connected brain networks compared to the acquaintance pairs. These findings challenge the conventional understanding that stronger social bonds lead to greater brain synchronization.
Published Scientists discover the cellular functions of a family of proteins integral to inflammatory diseases
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In a scientific breakthrough, researchers have revealed the biological mechanisms by which a family of proteins known as histone deacetylases (HDACs) activate immune system cells linked to inflammatory bowel disease (IBD) and other inflammatory diseases.
Published 3 in 5 parents play short order cook for young children who don't like family meal
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While most parents of preschool and elementary aged children strive to give their children a balanced, nutritional diet, some of their strategies to promote healthy eating may backfire, a national poll suggests.
Published Study explores possible future for early Alzheimer's diagnostics
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Digital memory test and a blood sample -- this combination will be tested for its potential to identify early Alzheimer's disease in a new research study. Over a hundred healthcare centers are part of the study that is now inviting participants to sign up. At least 3,000, preferably many more participants are needed for the study to be successful.
Published New approach to tackle muscle loss in aging
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A specific protein, TP53INP2, might prevent muscle loss associated with aging. A new study indicates that high levels of this protein are linked to greater muscle strength and healthier aging. This discovery paves the way for new treatments that could enhance the quality of life for the elderly.
Published Predicting cardiac arrhythmia 30 minutes before it happens
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Atrial fibrillation is the most common cardiac arrhythmia worldwide with around 59 million people concerned in 2019. This irregular heartbeat is associated with increased risks of heart failure, dementia and stroke. It constitutes a significant burden to healthcare systems, making its early detection and treatment a major goal. Researchers have recently developed a deep-learning model capable of predicting the transition from a normal cardiac rhythm to atrial fibrillation. It gives early warnings on average 30 minutes before onset, with an accuracy of around 80%. These results pave the way for integration into wearable technologies, allowing early interventions and better patient outcomes.