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Researchers are on a mission to kill drug-resistant bacteria, and a new study has identified a therapy that can penetrate the slime that such infections use to protect themselves from antibiotics.Researchers have shown that an antimicrobial peptide from cows has potential for treating incurable infections from the bacterium Klebsiella pneumoniae. The bacteria, commonly found in the intestines, is usually harmless. It becomes a health hazard when it enters other parts of the body and can cause pneumonia, urinary tract and wound infections. Those at highest risk include seniors and patients with other health problems such as diabetes, cancer, kidney failure and liver disease.

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A new device for taking blood samples uses microneedles and a suction cup instead of a large needle. People with a phobia of needles stand to benefit. More blood can be obtained than with the classic finger prick, making diagnostic measurements more reliable. Because the device can be produced at low cost, it is also suitable for developing countries.

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A study has identified a therapy that can penetrate the slime that such infections use to protect themselves from antibiotics. Scientists showed that an antimicrobial peptide from cows has potential for treating incurable infections from the bacterium Klebsiella pneumoniae. The bacteria, commonly found in the intestines, is usually harmless. It becomes a health hazard when it enters other parts of the body and can cause pneumonia, urinary tract and wound infections. Those at highest risk include seniors and patients with other health problems such as diabetes, cancer, kidney failure and liver disease.

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Combining time-restricted eating with high-intensity functional training may improve body composition and cardiometabolic parameters more than either alone, according to new research.

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Early detection has the potential to transform treatment and outcomes in cancer care, especially for cancers like liver cancer, which is typically diagnosed at a late stage with limited options for cure. A new study suggests that proteins detectable in the blood could improve predictions about risk of liver cancer years before typical diagnosis.

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There's a large and growing body of evidence pointing to potentially negative impacts of social media on mental health, from its addictive nature to disruptions in sleep patterns to effects on body image. Now, a new study has found that young women who took a social media break for as little as one week had a significant boost in self-esteem and body image -- particularly those most vulnerable to thin-ideal internalization.

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Human embryo compaction, an essential step in the first days of an embryo's development, is driven by the contractility of its cells. These results contradict the presupposed driving role of cell adhesion in this phenomenon and pave the way for improved assisted reproductive technology (ART).

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An mRNA cancer vaccine quickly reprogrammed the immune system to attack the most aggressive type of brain tumor in a first-ever human clinical trial.

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Researchers changed the composition of the gut microbiota in male mice through common antibiotics, inducing a condition called dysbiosis, and found that: - Mouse pups sired by a dysbiotic father show significantly lower birth weight, and have increased risk of growth disorders and postnatal mortality.

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Researchers have identified a causal genetic variant strongly associated with childhood obesity. The study provides new insight into the importance of the hypothalamus of the brain and its role in common childhood obesity and the target gene may serve as a druggable target for future therapeutic interventions.

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The health benefits of exercise are well known but new research shows that the body's response to exercise is more complex and far-reaching than previously thought. In a study on rats, a team of scientists has found that physical activity causes many cellular and molecular changes in all 19 of the organs they studied in the animals.

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The team discovered that an essential nutrient called choline is transported into the brain, across the blood-brain barrier, by a protein transporter called FLVCR2. This is discovery will inform future design of drugs for diseases such as Alzheimer's and stroke, mimicking choline so they can be smuggled into the brain.

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Women are 40% more likely to experience depression in the perimenopause than those who aren't experiencing any menopausal symptoms, finds a new study.

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Researchers have identified a novel Heat Shock Factor (HSF), designated as HSF5, which plays a crucial role in the completion of meiosis and the activation of genes essential for sperm formation. This discovery provides valuable insights into underlying causes of spermatogenic failure, the major contributor to male infertility. Furthermore, unlike other typical Heat Shock Factors, which primarily regulate gene expression in response to stress, such as heat shock, HSF5 plays a specific role in male germ production during meiosis under non-stress conditions.

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A simple blood test could allow doctors to determine whether a person may be at higher risk for stroke or cognitive decline during their lifetime, according to a new study.

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In an effort to improve delivery of costly medical treatments, a team of researchers in electrical engineering has developed a stimulating method that could make the human body more receptive to certain gene therapies.

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An undergraduate student turns her honor's thesis into a peer-reviewed publication on schizophrenia research.

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Researchers have discovered that the enzyme cyclophilin A, which is produced in large amounts in hematopoietic stem cells, is key for these cells to retain their regenerative potential and avert the effects of aging via an unexpected mechanism.

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Loneliness in adulthood follows a U-shaped pattern: it's higher in younger and older adulthood, and lowest during middle adulthood, reports a new study that examined nine longitudinal studies from around the world. The study also identified several risk factors for heightened loneliness across the whole lifespan, including social isolation, education and physical impairment.

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A genetic propensity to higher circulating levels of lipids containing arachidonic acid, an omega-6 polyunsaturated fatty acid found in eggs, poultry, and seafood, has been found to be linked with a lower risk for bipolar disorder. This new evidence paves the way for potential lifestyle or dietary interventions.