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Published Shoe technology reduces risk of diabetic foot ulcers
(via sciencedaily.com) Original source Researchers have developed a new shoe insole technology that helps reduce the risk of diabetic foot ulcers, a dangerous open sore that can lead to hospitalization and leg, foot or toe amputations.
Published Glial hyper-drive for triggering epileptic seizures
(via sciencedaily.com) Original source When epileptic patients suffer seizures, their brain is undergoing repetitive and excessive neuronal firing. But what triggers this has stumped scientists for years. Now, researchers have used fluorescence calcium sensors to track astrocytes' role in epileptic seizures, finding that that astrocyte activity starts approximately 20 seconds before the onset of epileptic neuronal hyperactivity.
Published Toxic chemicals from microplastics can be absorbed through skin
(via sciencedaily.com) Original source Toxic chemicals used to flame-proof plastic materials can be absorbed into the body through skin, via contact with microplastics, new research shows.
Published Dietary treatment more effective than medicines in IBS
(via sciencedaily.com) Original source Dietary treatment is more effective than medications in irritable bowel syndrome (IBS). With dietary adjustments, more than seven out of ten patients had significantly reduced symptoms.
Published Signs of multiple sclerosis show up in blood years before symptoms
(via sciencedaily.com) Original source In a discovery that could hasten treatment for patients with multiple sclerosis (MS), scientists have discovered a harbinger in the blood of some people who later went on to develop the disease.
Published Analyzing the progression in retinal thickness could predict cognitive progression in Parkinson's patients
(via sciencedaily.com) Original source Although there are still some aspects pending confirmation for its use in the clinical setting, and its resolution needs to be improved slightly, a study has shown that a method routinely used to carry out ophthalmological tests can also be used to monitor the neurodegeneration that occurs in Parkinson's patients. In the course of the research it was found that the neurodegeneration of the retina probably precedes cognitive impairment.
Published Coal train pollution increases health risks and disparities
(via sciencedaily.com) Original source The first health impact study of coal train pollution centers on the San Francisco Bay Area, with scientists finding communities near passing coal trains suffer worse health outcomes.
Published Metabolic health before vaccination determines effectiveness of anti-flu response
(via sciencedaily.com) Original source The annual influenza vaccine has become less effective on average over time. One reason may be reduced vaccine efficacy in people with obesity than those with a healthier body mass index (BMI), while the number of people with high BMI grows. Findings showed switching mice to a healthy diet four weeks before influenza vaccination protected 100% from a later flu exposure, despite still having a high BMI.
Published Perfect balance: How the brain fine-tunes its sensitivity
(via sciencedaily.com) Original source A sensitive perception of the environment is crucial for guiding our behavior. However, an overly sensitive response of the brain's neural circuits to stimuli can lead to neurodevelopmental disorders such as epilepsy. Researchers now report how neuronal networks in the mouse brain are fine-tuned.
Published Scientists uncover 95 regions of the genome linked to PTSD
(via sciencedaily.com) Original source In posttraumatic stress disorder (PTSD), intrusive thoughts, changes in mood, and other symptoms after exposure to trauma can greatly impact a person's quality of life. About 6 percent of people who experience trauma develop the disorder, but scientists don't yet understand the neurobiology underlying PTSD. Now, a new genetic study of more than 1.2 million people has pinpointed 95 loci, or locations in the genome, that are associated with risk of developing PTSD, including 80 that had not been previously identified.
Published How data provided by fitness trackers and smartphones can help people with MS
(via sciencedaily.com) Original source Monitoring and treating a case of multiple sclerosis requires reliable and long-term data on how the disease is progressing in the person in question. Fitness trackers and smartphones can supply this data, as a research team has now shown.
Published Siblings with unique genetic change help scientists progress drug search for type 1 diabetes
(via sciencedaily.com) Original source Two siblings who have the only known mutations in a key gene anywhere in the world have helped scientists gain new insights that could help progress the search for new treatments in type 1 diabetes.
Published Paper: To understand cognition--and its dysfunction--neuroscientists must learn its rhythms
(via sciencedaily.com) Original source Thought emerges and is controlled in the brain via the rhythmically and spatially coordinated activity of millions of neurons, scientists argue in a new article. Understanding cognition and its disorders requires studying it at that level.
Published Protecting brain cells with cannabinol
(via sciencedaily.com) Original source Scientists created four cannabis-derived CBN analogs (chemical look-a-likes) with enhanced neuroprotective properties and potential for therapeutic application in neurological disorders like Alzheimer's, Parkinson's, and traumatic brain injury. Their findings reveal novel aspects of CBN's neuroprotective activity and demonstrate the clinical potential of CBN and value of studying its analogs.
Published Guidance on energy and macronutrients across the lifespan
(via sciencedaily.com) Original source In the long history of recommendations for nutritional intake, current research is trending toward the concept of 'food as medicine' -- a philosophy in which food and nutrition are positioned within interventions to support health and wellness.
Published Calorie restriction study reveals complexities in how diet impacts aging
(via sciencedaily.com) Original source The rate at which human cells age is influenced by multiple interconnected factors. New research examined how restricting calories influences telomere length and biological aging.
Published New data identifies trends in accidental opioid overdoses in children
(via sciencedaily.com) Original source The US saw a 22% decline in rates of prescription-opioid overdose related emergency department (ED) visits in children 17 and younger between 2008 and 2019, but an uptick in the early part of the COVID-19 pandemic, according to a new study. The authors also note that rates of pediatric opioid overdoses remain high in many populations.
Published Artificial Intelligence beats doctors in accurately assessing eye problems
(via sciencedaily.com) Original source A study has found that the AI model GPT-4 significantly exceeds the ability of non-specialist doctors to assess eye problems and provide advice.
Published Researchers find that accelerated aging biology in the placenta contributes to a rare form of pregnancy-related heart failure
(via sciencedaily.com) Original source In a new study, researchers show that elevated levels of proteins related to cellular senescence, or aging, in the blood and the placenta are linked to this form of heart failure.
Published Workings of working memory detailed
(via sciencedaily.com) Original source Investigators have discovered how brain cells responsible for working memory -- the type required to remember a phone number long enough to dial it -- coordinate intentional focus and short-term storage of information.