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Published Extreme heat associated with children's asthma hospital visits
(via sciencedaily.com) Extreme heat events were associated with increased asthma hospital visits, according to new research.
Published New mechanisms behind antibiotic resistance
(via sciencedaily.com) Two newly discovered mechanisms in bacteria have been identified that can contribute to the development of antibiotic resistance. Changing the number of copies of resistance genes in bacteria increases antibiotic resistance, and can do so very quickly. These two mechanisms, along with a third known mechanism, can occur independently of each other, even within the same bacterial cell.
Published Scientists uncover promising treatment target for resistant brain cancer
(via sciencedaily.com) For many patients with a deadly type of brain cancer called glioblastoma, chemotherapy resistance is a big problem. But now, researchers may have moved a step closer to a solution.
Published Significant gaps between science of obesity and the care patients receive
(via sciencedaily.com) More than 40% of adults in the United States live with obesity, and the percentage of people living with obesity continues to increase dramatically. While experts have learned a great deal about the causes of obesity and effective treatments for it, that information isn't always implemented in clinical settings, which may be hindering progress in reducing the rates of cardiovascular disease.
Published Better medical record-keeping needed to fight antibiotic overuse
(via sciencedaily.com) Original source A lack of detailed record-keeping in clinics and emergency departments may be getting in the way of reducing the inappropriate use of antibiotics, a pair of new studies suggests. In one of the studies, about 10% of children and 35% of adults who got an antibiotic prescription during an office visit had no specific reason for the antibiotic in their record.
Published Global life expectancy to increase by nearly 5 years by 2050 despite geopolitical, metabolic, and environmental threats
(via sciencedaily.com) Original source The latest findings forecast that global life expectancy will increase by 4.9 years in males and 4.2 years in females between 2022 and 2050. Increases are expected to be largest in countries where life expectancy is lower, contributing to a convergence of increased life expectancy across geographies. The trend is largely driven by public health measures that have prevented and improved survival rates from cardiovascular diseases, COVID-19, and a range of communicable, maternal, neonatal, and nutritional diseases (CMNNs).
Published Clinicians report success with first test of drug in a patient with life-threatening blood clotting disorder
(via sciencedaily.com) Original source A recombinant form of human ADAMTS13 approved for a different condition helped to save the life of a young mother with immune thrombotic thrombocytopenic purpura.
Published Sweet taste receptor affects how glucose is handled metabolically by humans
(via sciencedaily.com) Original source The sweet-taste receptor might be the first stop in a metabolic surveillance system for sugar. The receptor is also expressed in certain intestinal cells, where it may facilitate glucose absorption and assimilation, as part of this system. A team found that stimulation and inhibition of the sweet receptor helps regulate glucose metabolism in humans and may have implications for managing such metabolic disorders as diabetes.
Published New AI tool to help beat brain tumors
(via sciencedaily.com) Original source A new AI tool to more quickly and accurately classify brain tumors has been developed.
Published Researchers develop 'game-changing' blood test for stroke detection
(via sciencedaily.com) Original source Stroke is the leading cause of disability worldwide and the second leading cause of death, but the right early intervention can prevent severe consequences. Scientists developed a new test by combining blood-based biomarkers with a clinical score to identify patients experiencing large vessel occlusion (LVO) stroke with high accuracy.
Published Large language models can't effectively recognize users' motivation, but can support behavior change for those ready to act
(via sciencedaily.com) Original source Large language model-based chatbots can't effectively recognize users' motivation when they are hesitant about making healthy behavior changes, but they can support those who are committed to take action, say researchers.
Published Different brain structures in females lead to more severe cognitive deficits after concussion than males
(via sciencedaily.com) Original source Important brain structures that are key for signaling in the brain are narrower and less dense in females, and more likely to be damaged by brain injuries, such as concussion. Long-term cognitive deficits occur when the signals between brain structures weaken due to the injury. The structural differences in male and female brains might explain why females are more prone to concussions and experience longer recovery from the injury than their male counterparts.
Published The vicious cycle of protein clumping in Alzheimer's disease and normal aging
(via sciencedaily.com) Original source To date, approaches to treatments for Alzheimer's disease have not addressed the contribution of protein insolubility as a general phenomenon, instead focusing on one or two insoluble proteins. Researchers have recently completed a systematic study in worms that paints an intricate picture of the connections between insoluble proteins in neurodegenerative diseases and aging. Furthermore, the work demonstrated an intervention that could reverse the toxic effects of the aggregates by boosting mitochondrial health.
Published Unique brain circuit is linked to Body Mass Index
(via sciencedaily.com) Original source Why can some people easily stop eating when they are full and others can't, which can lead to obesity? A new study has found one reason may be a newly discovered structural connection between two regions in the brain that appears to be involved in regulating feeding behavior. These regions involve the sense of smell and behavior motivation.The weaker the connection between these two brain regions, the higher a person's Body Mass Index, the scientists report.
Published Under stress, an observer is more likely to help the victim than to punish the perpetrator
(via sciencedaily.com) Original source Being stressed while witnessing injustice may push your brain towards altruism, according to a new study.
Published Researchers wrestle with accuracy of AI technology used to create new drug candidates
(via sciencedaily.com) Original source Researchers have determined that a protein prediction technology can yield accurate results in the hunt to efficiently find the best possible drug candidates for many conditions.
Published New gene delivery vehicle shows promise for human brain gene therapy
(via sciencedaily.com) Original source In an important step toward more effective gene therapies for brain diseases, researchers have engineered a gene-delivery vehicle that uses a human protein to efficiently cross the blood-brain barrier and deliver a disease-relevant gene to the brain in mice expressing the human protein. Because the vehicle binds to a well-studied protein in the blood-brain barrier, the scientists say it has a good chance at working in patients.
Published Natural toxins in food: Many people are not aware of the health risks
(via sciencedaily.com) Original source Many people are concerned about residues of chemicals, contaminants or microplastics in their food. However, it is less well known that many foods also contain toxins of completely natural origin. These are often chemical compounds that plants use to ward off predators such as insects or microorganisms. These substances are found in beans and potatoes, for example, and can pose potential health risks.
Published Singing repairs the language network of the brain after a cerebrovascular accident
(via sciencedaily.com) Original source Singing rehabilitates speech production in post-stroke aphasia. Researchers investigated the rehabilitative effect of singing on the brain.
Published Celiac disease: New findings on the effects of gluten
(via sciencedaily.com) Original source Celiac disease is a chronic autoimmune condition that occurs in around one per cent of the world's population. It is triggered by the consumption of gluten proteins from wheat, barley, rye and some oats. A gluten-free diet protects celiac patients from severe intestinal damage.