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Neuropathy, the nerve damage that causes pain and numbness in the feet and hands and can eventually lead to falls, infection and even amputation, is very common and underdiagnosed, according to a new study.

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A tiny, flexible electronic device that wraps around the spinal cord could represent a new approach to the treatment of spinal injuries, which can cause profound disability and paralysis. A team of engineers, neuroscientists and surgeons developed the devices and used them to record the nerve signals going back and forth between the brain and the spinal cord. Unlike current approaches, the new devices can record 360-degree information, giving a complete picture of spinal cord activity.

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Experts released a new clinical guideline for effectively managing individuals diagnosed with hypertrophic cardiomyopathy (HCM). The guideline reiterates the importance of collaborative decision-making with patients who have HCM and provides updated recommendations for the most effective treatment pathways for adult and pediatric patients.

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Psychiatrists and mental health professionals have a new standard for managing major depression, thanks to refreshed clinical guidelines.

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Researchers have found evidence of the molecular causes of the damaging impact heat stress causes on the gut, liver and brain in the elderly. These findings point to the potential of developing precise prognostic and therapeutic interventions.

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Starting people with opioid use disorder on extended-release, injectable naltrexone (XR-naltrexone) within five to seven days of seeking treatment is more effective than the standard treatment method of starting within 10-15 days, but requires closer medical supervision, according to results from a clinical trial. The findings suggest that this rapid treatment protocol could make XR-naltrexone more viable as a treatment option for opioid use disorder, which continues to take lives at an alarming rate.

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In people's early- to mid-20s, they reach what is called peak bone mineral density, which is higher for men than it is for women, according to researchers. This peak is one of the main determinants of fracture risk later in life. After reaching this peak, a person's bone density remains roughly stable for a couple of decades. Then, when women enter the menopausal transition, they experience accelerated bone loss. Men also experience bone density decline as they age. Sleep patterns also evolve over time.

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Emergency departments nationwide are overcrowded and overtaxed, but a new study suggests artificial intelligence (AI) could one day help prioritize which patients need treatment most urgently.

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Researchers have discovered a protein marker to help identify cells able to repopulate in patients with damaged blood vessels. Their findings could lead to new therapies for people with endothelial dysfunction, a type of disorder that contributes to coronary artery disease that may occlude with plaque and lack ability to carry sufficient blood into the heart tissue causing a heart attack.

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According to a recent study, high levels of sedentary behavior and physical inactivity from childhood strain the heart in adolescence. High cardiac workload predicts heart failure and other heart diseases. In light of the findings, increasing moderate and vigorous physical activity from childhood onwards is particularly important in preventing heart diseases.

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Recent reproductive research has opened the door for new treatments for solid cancer tumors, including breast cancer, lung cancer and melanoma.

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Fatty liver disease often leads to chronic liver inflammation and can even result in liver cancer. Scientists have now shown in mice that intermittent fasting on a 5:2 schedule can halt this development. The fasting regime reduces the development of liver cancer in mice with pre-existing liver inflammation. The researchers identified two proteins in liver cells that are jointly responsible for the protective effect of fasting. An approved drug can partially mimic this effect.

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In one of the first studies of its kind, UC Santa Barbara researchers have found that the immune status of postpartum mothers shifts with how she feeds her baby. Certain inflammatory proteins -- substances that are secreted as part of an immune response -- peak at different times of day, correlating with whether the mothers breastfeed, pump or formula-feed their babies.

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The world's largest study of cerebral palsy (CP) genetics has discovered genetic defects are most likely responsible for more than a quarter of cases in Chinese children, rather than a lack of oxygen at birth as previously thought.

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In an exploratory clinical trial, four male patients diagnosed with major depressive disorder underwent eight weeks of treatment with a device that generates a low-frequency ultralow magnetic field environment (ELF-ELME). An improvement in depressive symptoms was observed, with no adverse effects, among all patients. If the efficacy of the device can be confirmed in larger clinical trials with a control group, this therapy could serve as an alternative treatment for patients who do not want to take antidepressant medications.

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A new type of surgically implanted pump that can support a child's failing heart has passed the first stage of human testing in a recent trial.

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A sharp rise in exposures to synthetic cannabis products among youth -- some leading to hospitalization -- highlights the need for increased education around the dangers of exposure and increased focus on safe storage and packaging.

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Study suggests more extensive screening method in the first trimester of pregnancy may improve detection of preeclampsia.

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The toll cancer takes on lives in the U.S. has declined during the last 28 years, but not equitably. Disparities persist in many historically marginalized communities -- including communities disadvantaged by race, socioeconomic status, orientation or gender identity, and geographic location -- despite community outreach and engagement programs designed to address them.

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A new study provides some of the clearest and most comprehensive evidence to date on what is known about stress physiology and 'epigenetic programming.'