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Published Breast cancer rates rising among Canadian women in their 20s, 30s and 40s
(via sciencedaily.com) Original source Rates of breast cancer in women under the age of 50 are rising in Canada according to a study which showed an increase in breast cancer diagnoses among females in their twenties, thirties, and forties.
Published How geography acts as a structural determinant of health
(via sciencedaily.com) Original source In unincorporated communities in the United States-Mexico borderlands, historically and socially marginalized populations become invisible to the healthcare system, showing that geography acts as a structural determinant of health for low-income populations.
Published Air pollution and depression linked with heart disease deaths in middle-aged adults
(via sciencedaily.com) Original source A study in more than 3,000 US counties, with 315 million residents, has suggested that air pollution is linked with stress and depression, putting under-65-year-olds at increased risk of dying from cardiovascular disease.
Published Climb stairs to live longer
(via sciencedaily.com) Original source Climbing stairs is associated with a longer life, according to new research
Published Advance in the treatment of acute heart failure identified
(via sciencedaily.com) Original source A multicenter study has identified a potential new treatment for acute heart failure, a leading cause of hospitalization and death.
Published RNA modification is responsible for the disruption of mitochondrial protein synthesis in Alzheimer's disease
(via sciencedaily.com) Original source A team of researchers has identified a mechanism that causes mitochondrial dysfunction in Alzheimer's patients resulting in a reduction of the supply of energy to the brain.
Published Shoulder surgeons should rethink a common practice, study suggests
(via sciencedaily.com) Original source Many surgeons remove the bursa when repairing rotator cuff injuries, but a new animal study suggests that the small tissue helps with healing.
Published Vitamin D alters mouse gut bacteria to give better cancer immunity
(via sciencedaily.com) Original source Researchers have found that vitamin D encourages the growth of a type of gut bacteria in mice which improves immunity to cancer.
Published Food in sight? The liver is ready!
(via sciencedaily.com) Original source What happens in the body when we are hungry and see and smell food? A team of researchers has now been able to show in mice that adaptations in the liver mitochondria take place after only a few minutes. Stimulated by the activation of a group of nerve cells in the brain, the mitochondria of the liver cells change and prepare the liver for the adaptation of the sugar metabolism. The findings could open up new avenues for the treatment of type 2 diabetes.
Published Nanomaterial that mimics proteins could be basis for new neurodegenerative disease treatments
(via sciencedaily.com) Original source A newly developed nanomaterial that mimics the behavior of proteins could be an effective tool for treating Alzheimer's and other neurodegenerative diseases. The nanomaterial alters the interaction between two key proteins in brain cells -- with a potentially powerful therapeutic effect.
Published Identifying a new liver defender: The role of resident macrophages
(via sciencedaily.com) Original source Researchers discovered liver resident macrophages' pivotal role in defending against gut bacteria and related substances entering via the portal vein, particularly under compromised intestinal barrier conditions. Identified as 'sentinel macrophages,' they are activated by isoallo-lithocholic acid. This finding holds promise for developing preventive and therapeutic strategies for liver chronic inflammatory diseases, such as metabolic dysfunction-associated steatohepatitis (MASH), by enhancing the function of these macrophages to mitigate inflammation and improve treatment efficacy.
Published Diamond dust shines bright in Magnetic Resonance Imaging
(via sciencedaily.com) Original source An unexpected discovery surprised a scientist: nanometer-sized diamond particles, which were intended for a completely different purpose, shone brightly in a magnetic resonance imaging experiment -- much brighter than the actual contrast agent, the heavy metal gadolinium. Could diamond dust -- in addition to its use in drug delivery to treat tumor cells -- one day become a novel contrast agent used for MRI?
Published Physical activity in nature helps prevent several diseases, including depression and type 2 diabetes
(via sciencedaily.com) Original source Physical activity in natural environments prevent almost 13,000 cases of non-communicable diseases a year in England and save treatment costs of more than 100 million, new research has found.
Published Genetic variations may predispose people to Parkinson's disease following long-term pesticide exposure, study finds
(via sciencedaily.com) Original source A new study found certain genetic variants could help explain how long-term pesticide exposure could increase the risk of Parkinson's disease.
Published Simplified diagnosis of rare eye diseases
(via sciencedaily.com) Original source Uveitis is a rare inflammatory eye disease. Posterior and panuveitis in particular are associated with a poor prognosis and a protracted course of the disease. Diagnosis and monitoring can be challenging for healthcare professionals. Fundus autofluorescence (FAF) is a fast and non-invasive imaging technique that supports this. Researchers have drafted a review on how FAF can facilitate the diagnosis and monitoring of posterior uveitis and panuveitis.
Published AI in medicine: The causality frontier
(via sciencedaily.com) Original source Machines can learn not only to make predictions, but also to handle causal relationships. An international research team shows how this could make therapies safer, more efficient, and more individualized.
Published Maternal grandmothers' support buffers children against the impacts of adversity
(via sciencedaily.com) Original source A study shows that investment by maternal grandmothers can improve the well-being of grandchildren who have faced adversities in life. The positive effects can last well into adulthood.
Published National trial safely scaled back prescribing of a powerful antipsychotic for the elderly
(via sciencedaily.com) Original source Warning letters can safely cut prescribing of a powerful but risky antipsychotic, according to a new study. Researchers used Medicare data to study the effects of the letters on hundreds of thousands of older adults with dementia. They found a significant and lasting reduction in prescribing but no signs of adverse effects on patient health.
Published Solving the riddle of the sphingolipids in coronary artery disease
(via sciencedaily.com) Original source Investigators have uncovered a way to unleash in blood vessels the protective effects of a type of fat-related molecule known as a sphingolipid, suggesting a promising new strategy for the treatment of coronary artery disease.
Published Use of acid reflux drugs linked to higher risk of migraine
(via sciencedaily.com) Original source People who take acid-reducing drugs may have a higher risk of migraine and other severe headache than people who do not take these medications, according to a new study. The acid-reducing drugs include proton pump inhibitors such as omeprazole and esomeprazole, histamine H2-receptor antagonists, or H2 blockers, such as cimetidine and famotidine, and antacid supplements.