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Published Melanoma in darker skin tones
(via sciencedaily.com) Original source Melanoma, an aggressive form of skin cancer that accounts for 75% of all skin-cancer-related deaths, is often detected later in people with darker skin complexions -- and the consequences can be devastating, a new study reveals.
Published Breakthrough in hemostasis and wound healing research
(via sciencedaily.com) Original source A breakthrough study features a biomedical engineering innovation with the potential to transform trauma care and surgical practices. A scientific research team has developed platelet-like particles that integrate into the body's clotting pathways to stop hemorrhage.
Published Metabolism of autism reveals developmental origins
(via sciencedaily.com) Original source Researchers have shed new light on the changes in metabolism that occur between birth and the presentation of autism spectrum disorder (ASD) later in childhood. The researchers discovered that a small number of biochemical pathways are responsible for the majority of these changes, which could help inform new early detection and prevention strategies for autism.
Published New tool to boost battle against childhood undernutrition
(via sciencedaily.com) Original source The tool will help researchers better understand major challenges that afflict undernourished children, such as changes in cognitive development and higher infection rates.
Published Discrimination may accelerate aging
(via sciencedaily.com) Original source Discrimination may speed up the biological processes of aging, according to a new study.
Published New treatment could reverse hair loss caused by an autoimmune skin disease
(via sciencedaily.com) Original source Researchers developed a potential new treatment for alopecia areata, an autoimmune disorder that causes hair loss. The microneedle patch delivers immune-regulating molecules that can teach T cells not to attack hair follicles, helping hair regrow.
Published How night shift work can raise risk of diabetes, obesity
(via sciencedaily.com) Original source Just a few days on a night shift schedule throws off protein rhythms related to blood glucose regulation, energy metabolism and inflammation, processes that can influence the development of chronic metabolic conditions. The finding provides new clues as to why night shift workers are more prone to diabetes, obesity and other metabolic disorders. Though more research is needed, the researchers said the study shows that these disrupted rhythms can be seen in as little as three days, which suggests early intervention to prevent diabetes and obesity is possible. Such intervention could also help lower the risk of heart disease and stroke, which is elevated in night shift workers as well.
Published AI advancements make the leap into 3D pathology possible
(via sciencedaily.com) Original source Researchers present Tripath: new, deep learning models that can use 3D pathology datasets to make clinical outcome predictions. The research team imaged curated prostate cancer specimens, using two 3D high-resolution imaging techniques. The models were then trained to predict prostate cancer recurrence risk on volumetric human tissue biopsies. By comprehensively capturing 3D morphologies from the entire tissue volume, Tripath performed better than pathologists and outperformed deep learning models that rely on 2D morphology and thin tissue slices.
Published How biological aging clocks tick
(via sciencedaily.com) Original source Aging clocks can measure the biological age of humans with high precision. Biological age can be influenced by environmental factors such as smoking or diet, thus deviating from the chronological age that is calculated using the date of birth. The precision of these aging clocks suggests that the aging process follows a program. Scientists have now discovered that aging clocks actually measure the increase in stochastic changes in cells.
Published 'Digital afterlife': Call for safeguards to prevent unwanted 'hauntings' by AI chatbots of dead loved ones
(via sciencedaily.com) Original source Researchers lay out the need for design safety protocols that prevent the emerging 'digital afterlife industry' causing social and psychological harm.
Published Who should receive preventive treatment for TB? Individuals of all ages with positive skin or blood test
(via sciencedaily.com) Original source Researcher found that exposed individuals with confirmed TB infection -- i.e. a positive skin or blood test -- should receive priority treatment in settings with a low prevalence of the disease, regardless of their age. However, in high-burden settings, all exposed individuals should be considered for preventative treatment, even without a confirmed infection. This strategy can help end the tuberculosis epidemic and support global public health efforts to reduce TB mortality by 95 percent by 2035 (from 2015 estimates).
Published Neuropathy very common, underdiagnosed
(via sciencedaily.com) Original source Neuropathy, the nerve damage that causes pain and numbness in the feet and hands and can eventually lead to falls, infection and even amputation, is very common and underdiagnosed, according to a new study.
Published 'Wraparound' implants represent new approach to treating spinal cord injuries
(via sciencedaily.com) Original source A tiny, flexible electronic device that wraps around the spinal cord could represent a new approach to the treatment of spinal injuries, which can cause profound disability and paralysis. A team of engineers, neuroscientists and surgeons developed the devices and used them to record the nerve signals going back and forth between the brain and the spinal cord. Unlike current approaches, the new devices can record 360-degree information, giving a complete picture of spinal cord activity.
Published Exercise, new drug class recommended for management of hypertrophic cardiomyopathy
(via sciencedaily.com) Original source Experts released a new clinical guideline for effectively managing individuals diagnosed with hypertrophic cardiomyopathy (HCM). The guideline reiterates the importance of collaborative decision-making with patients who have HCM and provides updated recommendations for the most effective treatment pathways for adult and pediatric patients.
Published Teens who view their homes as more chaotic than their siblings have poorer mental health in adulthood
(via sciencedaily.com) Original source Adolescents who view their households as more unstructured, disorganized, or hectic than their siblings develop more mental health and behavioral problems in early adulthood, according to new research.
Published A tailored vaccine could one day treat eczema in children
(via sciencedaily.com) Original source New research suggests a 'tailored vaccine' might hold the key to treating bacteria-driven flares of eczema in children. The team has taken several leaps forward in understanding how the immune response works in cases of eczema driven by the common, troublesome Staphylococcus aureus bacterium, and in doing so they have identified new cellular targets for a vaccine.
Published New guidelines for depression care emphasize patient-centred approach
(via sciencedaily.com) Original source Psychiatrists and mental health professionals have a new standard for managing major depression, thanks to refreshed clinical guidelines.
Published Children sleep problems associated with psychosis in young adults
(via sciencedaily.com) Original source Children who experience chronic lack of sleep from infancy may be at increased risk of developing psychosis in early adulthood, new research shows.
Published Damaging impact of heat waves on vital organs
(via sciencedaily.com) Original source Researchers have found evidence of the molecular causes of the damaging impact heat stress causes on the gut, liver and brain in the elderly. These findings point to the potential of developing precise prognostic and therapeutic interventions.
Published Faster approach for starting extended-release naltrexone to treat opioid use disorder shown effective
(via sciencedaily.com) Original source Starting people with opioid use disorder on extended-release, injectable naltrexone (XR-naltrexone) within five to seven days of seeking treatment is more effective than the standard treatment method of starting within 10-15 days, but requires closer medical supervision, according to results from a clinical trial. The findings suggest that this rapid treatment protocol could make XR-naltrexone more viable as a treatment option for opioid use disorder, which continues to take lives at an alarming rate.