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Published Drug limits dangerous reactions to allergy-triggering foods, Stanford Medicine-led study of kids finds (via sciencedaily.com) Original source
A drug that binds to allergy-causing antibodies can protect children from dangerous reactions to accidentally eating allergy-triggering foods, a new study found.
Published Hearing relaxing words in your sleep slows your heart down (via sciencedaily.com) Original source
Researchers have investigated whether the body is truly disconnected from the external world during sleep. To do so, they focused on how heartbeat changes when we hear different words during sleep. They found that relaxing words slowed down cardiac activity as a reflection of deeper sleep and in comparison to neutral words that did not have such a slowing effect. This discovery sheds new light on brain-heart interactions during sleep.
Published Similarities and differences in human and insect vision formation (via sciencedaily.com) Original source
Researchers have discovered profound similarities and surprising differences between humans and insects in the production of the critical light-absorbing molecule of the retina, 11-cis-retinal, also known as the 'visual chromophore.' The findings deepen understanding of how mutations in the RPE65 enzyme cause retinal diseases, especially Leber congenital amaurosis, a devastating childhood blinding disease.
Published Metabolic diseases may be driven by gut microbiome, loss of ovarian hormones (via sciencedaily.com) Original source
Mice that received fecal implants from donors that had their ovaries removed gained more fat mass and had greater expression of liver genes associated with inflammation, Type 2 diabetes, fatty liver disease and atherosclerosis. The findings may shed light on the greater incidence of metabolic dysfunction in postmenopausal women.
Published Cracking the code of neurodegeneration: New model identifies potential therapeutic target (via sciencedaily.com) Original source
Scientists have developed an innovative neural cell culture model, shedding light on the intricate mechanisms underlying neurodegeneration. Their research pinpointed a misbehaving protein as a promising therapeutic target in the treatment of amyotrophic lateral sclerosis (ALS) and frontotemporal dementia (FTD).
Published Damage to cell membranes causes cell aging (via sciencedaily.com) Original source
Researchers have discovered that damage to the cell membrane promotes cellular senescence, or cell aging.
Published Treating newly-diagnosed Crohn's patients with advanced therapy leads to dramatic improvements in outcomes (via sciencedaily.com) Original source
A large-scale clinical trial of treatment strategies for Crohn's disease has shown that offering early advanced therapy to all patients straight after diagnosis can drastically improve outcomes, including by reducing the number of people requiring urgent abdominal surgery for treatment of their disease by ten-fold.
Published Uncovering anxiety: Scientists identify causative pathway and potential cures (via sciencedaily.com) Original source
Quick-acting targeted therapies with minimal side effects are an urgent need for the treatment of anxiety-related disorders. While delta opioid receptor (DOP) agonists have shown 'anxiolytic' or anxiety-reducing effects, their mechanism of action is not well-understood. A new study highlights the role of specific neuronal circuits in the brain involved in the development of anxiety, and distinct mechanisms of action of the therapeutic DOP agonist -- KNT-127.
Published How children's birthdays help show the best month for flu shots (via sciencedaily.com) Original source
First large-scale analysis of optimal timing for flu shots finds October is the best month for children to get vaccinated against influenza. Study of 800,000 pediatrician visits leverages links between children's birth month, annual physical schedule, and vaccination timing.
Published Air pollution linked to more signs of Alzheimer's in brain (via sciencedaily.com) Original source
People with higher exposure to traffic-related air pollution were more likely to have high amounts of amyloid plaques in their brains associated with Alzheimer's disease after death, according to a new study. Researchers looked at fine particulate matter, PM2.5, which consists of pollutant particles of less than 2.5 microns in diameter suspended in air.
Published Blood test could determine diabetes risks (via sciencedaily.com) Original source
A blood test could potentially be used to assess a patient's risk of type 2 diabetes, a new study has found.
Published How does the brain make decisions? (via sciencedaily.com) Original source
Mouse study provides insights into communication between neurons during decision-making.
Published Possible trigger for autoimmune diseases discovered : B cells teach T cells which targets must not be attacked (via sciencedaily.com) Original source
Immune cells must learn not to attack the body itself. A team of researchers has discovered a previously unknown mechanism behind this: other immune cells, the B cells, contribute to the 'training' of the T cells in the thymus gland. If this process fails, autoimmune diseases can develop. The study confirms this for Neuromyelitis optica, a disease similar to Multiple Sclerosis. Other autoimmune diseases may be linked to the failure of this new mechanism as well.
Published How AI can help spot early risk factors for Alzheimer's disease (via sciencedaily.com) Original source
Scientists have found a way to predict Alzheimer's Disease up to seven years before symptoms appear by analyzing patient records with machine learning.
Published Detecting pathogens faster and more accurately by melting DNA (via sciencedaily.com) Original source
A new analysis method can detect pathogens in blood samples faster and more accurately than blood cultures, which are the current state of the art for infection diagnosis. The new method, called digital DNA melting analysis, can produce results in under six hours, whereas culture typically requires 15 hours to several days, depending on the pathogen.
Published Common hair loss and prostate drug may also cut heart disease risk in men and mice (via sciencedaily.com) Original source
The drug finasteride, also known as Propecia or Proscar, treats male pattern baldness and enlarged prostate in millions of men worldwide. But a new study suggests the drug may also provide a surprising and life-saving benefit: lowering cholesterol and cutting the overall risk of cardiovascular disease.
Published Avid appetite in childhood linked to later eating disorder symptoms (via sciencedaily.com) Original source
The study looked at survey data from 3,670 young people in the UK and the Netherlands to investigate how appetite traits in early childhood might relate to the likelihood of developing eating disorder symptoms up to 10 years later. The researchers found that a particularly high food responsiveness, defined as the urge to eat when you see, smell or taste palatable food, at the ages of four and five was linked to a higher likelihood of reporting a range of eating disorder symptoms at ages 12 to 14.
Published Red light can reduce blood glucose levels (via sciencedaily.com) Original source
Shining a specific frequency of red light on a person's back for 15 minutes can significantly reduce blood sugar levels, according to a new study.
Published Time watching videos may stunt toddler language development, but it depends on why they're watching (via sciencedaily.com) Original source
A new study reveals that passive video use among toddlers can negatively affect language development, but their caregiver's motivations for exposing them to digital media could also lessen the impact.
Published Bridging diet, microbes, and metabolism: Implications for metabolic disorders (via sciencedaily.com) Original source
Mounting evidence suggests that the secret to understanding human health and combating metabolic diseases lies hidden within the microscopic world of our gut bacteria. Recent research reveals that a specific fatty acid produced by gut bacteria directly influences fat metabolism in animals. This research is pivotal as it sheds light on the complex interplay between the diet, gut microbiota, and host metabolic health, offering insights that could open new avenues in our approach to managing metabolic disorders.